Work on the £32m development will start next month with completion expected in early 2027.
The specialist digital tech hub and the businesses located there will focus on digital technology with global AI firm Automatic Analytics among the founding firms set to take up residence.
Chris Yates, Yorkshire director at Willmott Dixon, said: “Our team of local commercial experts will bring a wealth of experience and innovation to Gateway One. In partnership with City of Doncaster Council, we will create a cutting-edge and sustainable hub where digital and technology businesses can thrive and grow in this city.
“We’re passionate that innovation will be a catalyst for creating opportunities for the people of Doncaster, so, in partnership with our proud local supply chain partners, we are committed to creating six new employment opportunities directly on the project.
“Through our bespoke ‘Building Lives Academy’ initiatives in collaboration with Advance Employment Hub, we also aim to deliver more than 650 hours of impactful employment support for local people furthest from the job market, those at risk of redundancy and those looking to transition into the construction industry.”